Immune Responses to AAV Vectors

A free, public event organized by FDA & ASGCT


January 24-25, 2023
11 a.m. – 3 p.m. (ET) each day

Topics will include, but are not limited to:

  • Appropriateness and utility of a companion diagnostic for assessing pre-existing immunity and requirements for product approval

  • Requirements for immunogenicity testing, including data that should be collected and what may be relied upon from previous applications, and recommendations on clinically meaningful metrics

Speakers & Topics

Jan. 24, 2023

  • Shari Gordon (AskBio)
    Overview of immunogenicity and clinical trials with healthy volunteers

  • J. Fraser Wright (Stanford University)
    Vector process and manufacturing: How does it impact immunogenicity?

  • Manuela Corti (University of Florida)
    Overview of readministration approaches

  • FDA speaker TBD

Jan. 25, 2023

  • Genevieve Laforet (Aspa Therapeutics)
    Complement activation in gene therapy trials

  • Carsten Bonnemann (NINDS/NIH)
    SAEs, complement activation, and anti-dystrophin responses

  • Terry Flotte (UMass Chan Medical School)
    GM2 trial for Tay-Sachs disease

  • Dave Copland (University of Bristol)
    Intraocular AAV inflammation

Please note: Topics will also be of interest to those in the gene therapy regulatory space.

Registration

If you have attended a previous ASGCT event, please sign into your account below. If this is your first time registering for an ASGCT event, you can create an account below.

Sign In to Register Create an Account to Register
2023

26th Annual Meeting

May 16-20 | Los Angeles, CA

This site uses cookies to offer you a better user experience and to analyze site traffic. By continuing to use this website, you accept our use of cookies.