The Molecular Therapy Podcast

Editors from the Molecular Therapy Family of Journals profile impactful research published in ASGCT's journals.

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Find insightful intervews, riveting conversations, and incredible discoveries on the ASGCT Podcast Network.

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Episodes

A New Era of Molecular Therapy with Joseph Glorioso, PhD

Drs.Herzog and Glorioso engage in a wide-ranging conversation that touches on the history of Molecular Therapy, highlights from the gene and cell therapy field, and how Molecular Therapy will continue to grow and evolve under Dr. Glorioso’s leadership.

CRISPR Editing and AAV Integration Outcomes in the Brain

Drs. Beverly Davidson and Bryan Simpson join MT EiC Dr. Roland Herzog to discuss their recent paper, Targeted long-read sequencing captures CRISPR editing and AAV integration outcomes in the brain, which was published in Molecular Therapy.

Targeting STAT3 in Tumors with Oligo-PROTAC

Drs. Paloma Giangrande and Marcin Kortylewski discuss a recent article published in Molecular Therapy Nucleic Acids by Dr. Kortylewski and colleagues titled "Oligo-PROTAC strategy for cell-selective and targeted degradation of activated STAT3."

AAV Capsid Production with Drs. Mario Mietzsch and Robert McKenna

Dr. Daniel Stone speaks with Drs. Mario Mietzsch and Robert McKenna from the University of Florida to discuss their recent article published in MTMCD's recent special issue Biomanufacturing in Gene and Cell Therapy titled "Production and characterization of an AAV1-VP3-only capsid: An analytical benchmark standard."

Meet Dr. Mohamed Abou-el-Enein, EiC of MTMCD

Mohamed Abou-el-Enein, MD, PhD, MSPH, the new editor-in-chief of Molecular Therapy Methods & Clinical Development (MTMCD), sits down with Scientific Editor Rory Bricker-Anthony, PhD, to discuss his vision for the journal.

mRNA Vaccines with Dr. Norbert Pardi

Dr. Norbert Pardi discusses a recent article published in the September issue of Molecular Therapy by Dr. Pardi and colleagues titled, "Development of an mRNA-lipid Nanoparticle Vaccine Against Lyme Disease."

Trap and Ambush with Dr. Richard Vile

Dr. Richard Vile discusses an article published in the June issue of Molecular Therapy Oncology by himself and colleagues titled, "Trap and ambush therapy using sequential primary and tumor escape-selective oncolytic viruses."

COVID-19 Diagnostics with Dr. Maxim Berezovski

Dr. Maxim Berezovski discusses a recent article he and colleagues published in Molecular Therapy Nucleic Acids, Discovery of DNA aptamers targeting SARS-CoV-2 nucleocapsid protein and protein-binding epitopes for label-free COVID-19 diagnostics.

Improving AAV Production with Drs. Adam Schieferecke and David Schaffer

Drs. David Schaffer and Adam Schieferecke discuss a recent article they published with colleagues in the February issue of Molecular Therapy titled, "Evolving membrane-associated accessory protein variants for improved adeno-associated virus production."

CAR T for Acute Myeloid Leukemia with Dr Marco Davila

Join Drs. Timothy Cripe and Marco Davila as they discuss a recent article published in the December issue of Molecular Therapy Oncology by Dr. Davila and colleagues titled, Bispecific CD33/CD123 targeted chimeric antigen receptor T cells for the treatment of acute myeloid leukemia.

2024

Breakthroughs in Muscular Dystrophy

November 19-20, 2024 | Chicago, IL