Agenda

(All times are CDT)

Tuesday, September 15

Keynote Address

8-8:30 a.m.—Anthony S. Fauci, M.D., Director, National Institute of Allergy and Infectious Diseases (NIAID)
COVID-19: The Research Response

Understanding SARS-CoV-2: Virology, Epidemiology, and Pathogenesis

Moderator: Stephen J. Russell, M.D., Ph.D.

8:30-9 a.m.—Susan Weiss, Ph.D., Professor and Vice Chair, Department of Microbiology
Co-Director, Penn Center for Research on Coronaviruses and Other Emerging Pathogens
Perelman School of Medicine, University of Pennsylvania
Overview of Coronaviruses

9-9:30 a.m.—Linfa Wang, Ph.D., Director of the Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore
Zoonotic Origins: Why bats?

9:30-10 a.m.—Jordan Tappero, M.D., M.P.H, Deputy Director, Global Health, Neglected Tropical Diseases
Bill & Melinda Gates Foundation
Epidemiology of COVID-19: A Global Perspective

10-10:30 a.m.—Tom Gallagher, Ph.D., Professor of Microbiology and Immunology, Loyola University Chicago
Virus Entry and Targets

10:30-11 a.m.—Jason McLellan, Ph.D., Associate Professor, Molecular Biosciences, The University of Texas at Austin
Structure and Design of SARS-CoV-2 Spikes

11-11:30 a.m.—Dan Barouch, M.D., Ph.D., William Bosworth Castle Professor of Medicine and Professor of Immunology at Harvard Medical School, Director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center
Pathogenesis

Diagnosing and Measuring Immune Responses to SARS-CoV-2 Infection

Moderator: Paul McCray, M.D.

1-1:30 p.m.—Janice Chen, Ph.D., Co-founder and CTO, Mammoth Biosciences
Diagnostic Approaches

1:30-2 p.m.—Stanley Perlman, M.D., Ph.D., Professor of Microbiology and Immunology, Professor of Pediatrics, Mark Stinski Chair in Virology, University of Iowa
Host Immune Response to CoVs: Friend or Foe?

2-2:30 p.m.—Galit Alter, Ph.D., Professor of Medicine at Harvard Medical School, Group Leader at the Ragon Institute of MGH, MIT and Harvard
Humoral Immune Response

Treatment of COVID-19

Moderator: Florian Krammer, Ph.D.

3-3:30 p.m.—Myron Cohen, M.D., Yeargan-Bate Distinguished Professor of Medicine, Microbiology and Immunology, and Epidemiology; Associate Vice Chancellor for Global Health and Medical Affairs; Director, Institute for Global Health & Infectious Diseases; UNC School of Medicine
Landscape of Monoclonal Antibody Therapies

3:30-4 p.m.—Erica Ollmann Saphire, Ph.D., Professor Adjunct, Department of Immunology and Microbiology, Scripps Research
Antibody Therapeutics against SARS-CoV-2: A Global Collaboration

4-4:30 p.m.—Mark Denison, M.D., Edward Claiborne Stahlman Professor of Pediatrics, Professor of Pathology, Microbiology and Immunology, and Director of the Division of Pediatric Infectious Diseases at Vanderbilt University Medical Center
SARS-CoV-2 Proteins as Targets for Therapies

4:30-5 p.m.—Michael Joyner, M.D., Anesthesiologist, Mayo Clinic
Convalescent Plasma Therapy

5-5:30 p.m.—Larry Corey, M.D., Past President and Director, Professor in the Vaccine and Infectious Disease Division, Principal Investigator in the HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center; Professor of Medicine and Laboratory Medicine, University of Washington
Strategies for Vaccine Development

Wednesday, September 16

SARS-CoV-2 Vaccines

Moderator: Rayne Rouce, M.D.

8-8:30 a.m.—Paul McCray, M.D., Professor of Pediatrics, Microbiology and Immunology, and Internal Medicine, University of Iowa
Rodent Models for SARS-CoV-2

8:30-9 a.m.—Vincent Munster, Ph.D., Chief, Virus Ecology Unit, National Institute of Allergy and Infectious Diseases (NIAID)
Primate Models for SARS-CoV-2

9-9:30 a.m.—Sarah Gilbert, Ph.D., Professor of Vaccinology, Nuffield Department of Medicine, University of Oxford; Co-founder of Vaccitech
Adenovirus Vaccine Candidates

9:30-10 a.m.—Florian Krammer, Ph.D., Professor of Vaccinology, Icahn School of Medicine at Mount Sinai
Vaccine Readouts: Analysis, Antibodies, and Immune Response

10-10:30 a.m.—Kizzmekia Corbett, Ph.D., Research Fellow in the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases (NIAID)
NIH VRC Efforts and RNA Vaccine Candidates

Abstract Presentations

Moderator: Terence R. Flotte, M.D.

The second day of programming will primarily be comprised of oral presentations of abstracts submitted to ASGCT during the Call for Abstracts. These abstracts will consist of brand new research relating to COVID-19 on topics such as diagnostics, vaccine strategies, and gene and cell therapies.

11-11:12 a.m.—Gaurav Sahay, Ph.D., Oregon State University
Rapid generation of circulating and mucosal decoy ACE2 using mRNA nanotherapeutics for the potential treatment of SARS-CoV-2

11:12-11:24 a.m.—Paul Ayoub, University of California, Los Angeles
Improved Spike Glycoproteins to Pseuodtype Lentiviral Vectors

11:24-11:36 a.m.—Saad Khan, Ph.D., Ottawa Hospital Research Institute
Cellular Immuno-Therapy for COVID-19 induced Acute Respiratory Distress Syndrome: Design of the CIRCA-19 Trial

11:36-11:48 a.m.—Robin Hu, University of Pennsylvania
Design of conditional small interfering RNA riboswitches to identify and selectively kill cells infected with SARS-CoV-2

11:48 a.m.-12 p.m.—Chanakha Navaratnarajah, Ph.D., Mayo Clinic
SARS-CoV-2 Spike Glycoprotein Activation in Cardiomyocytes: Mechanism and Pathological Consequences