We now know that cancer cells are not all alike, even within the same tumor mass, and that numerous types of normal cells are coopted to create a unique tumor microenvironment. Single-cell RNA sequencing (scRNAseq) is a powerful tool used for characterizing the individual transcriptional landscape of thousands of individual cells simultaneously. This method not only facilitates precise identification of cell types but also uncovers intracellular signaling pathways and intercellular communication. Insights gained from scRNAseq help us better understand tumor biology, find therapeutic vulnerabilities, and identify prognostic biomarkers.
Join us as David Coffey, Ryan Roberts, and Emil Lou discuss different applications of this powerful technology in cancer biology and therapeutics.
Moderator
Timothy Cripe, MD, PhD
Editor-in-chief, Molecular Therapy Oncology
Professor and Chief of Hematology/Oncology/BMT, Nationwide Children’s Hospital Professor of Pediatrics, The Ohio State University
Presenters
David Coffey, MD
Assistant Professor of Medicine
Sylvester Comprehensive Cancer Center, University Hospital of Miami, USA
Ryan Roberts, MD, PhD
Physician and Principal Investigator
Division of Hematology and Oncology and Abigail Wexner Research Institute, Nationwide Children’s Hospital, Columbus, USA
Emil Lou, MD, PhD
Professor of Medicine
Division of Hematology, Oncology, and Transplantation, University of Minnesota, USA